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Hepcidin Antimicrobial Peptide Antibody (LY2787106) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
LY2787106
Clonality
Monoclonal
Host
Human
Conjugate
Biotin

Order Details

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Hepcidin Antimicrobial Peptide Antibody (LY2787106) [Biotin] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Hepcidin / HAMP
Isotype
IgG4
Clonality
Monoclonal
Host
Human
Gene
HAMP
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for Hepcidin Antimicrobial Peptide Antibody (LY2787106) [Biotin]

  • HAMP
  • HEPC
  • hepcidin antimicrobial peptide
  • Hepcidin
  • HEPCPutative liver tumor regressor
  • HFE2B
  • HFE2Bhepcidin
  • LEAP1
  • LEAP-1
  • LEAP1PLTR
  • Liver-expressed antimicrobial peptide 1
  • PLTR

Background

The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HAMP