Glutathione Peroxidase 5 Antibody Summary
Immunogen |
Immunized with recombinant Rat Glutathione Peroxidase 5 (Uniprot#: P30710; Thr22-Ile221 (Uniprot#: P30710) |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
GPX5 |
Purity |
Antigen and protein A Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence 5-20ug/mL
- Immunohistochemistry 5-20ug/mL
- Western Blot 0.5-2ug/mL
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS, pH7.4, 50% glycerol |
Preservative |
0.02% Sodium Azide |
Concentration |
0.74 mg/ml |
Purity |
Antigen and protein A Affinity-purified |
Alternate Names for Glutathione Peroxidase 5 Antibody
Background
Glutathione peroxidase (GPX)/glutathione reductase is part of the hydrogen peroxide scavenging system found within the epididymis in the mammalian male reproductive tract. GPX5 expression is epididymis-specific and the transcript is unique from other GPXs because it contains a deletion resulting in an mRNA that does not contain a selenocysteine (UGA) codon (an unusual amino acid present in other GPXs). This deletion also renders the mRNA incapable of encoding an active GPX isoenzyme. For this reason, GPX5 is selenium-independent and has very little activity towards hydrogen peroxide or organic hydroperoxides. GPX5, which is bound to the acrosome of sperm, may act to protect sperm from premature acrosome reaction in the epididymis. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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