Mouse myeloma cell line NS0-derived recombinant human FGF R1 alpha (IIIc)
Specificity
Detects human FGF R1 in direct ELISAs and Western blots. Recognizes all isoforms of recombinant human (rh) FGF R1 and shows 10-25% cross-reactivity with various isoforms of rhFGF R2 and rhFGF R3.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
FGFR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for FGFR1 Antibody (133105) [Unconjugated]
basic fibroblast growth factor receptor 1
BFGFR
bFGF-R-1
CD331 antigen
CD331
CEK
EC 2.7.10
EC 2.7.10.1
FGF R1
FGFBR
FGFR1
FGFR-1
fibroblast growth factor receptor 1
FLGH3
FLJ99988
Flt-2
FLT2H4
Fms-like tyrosine kinase 2
fms-related tyrosine kinase 2
H2
H5
HBGFR
heparin-binding growth factor receptor
hydroxyaryl-protein kinase
KAL 2
KAL2
N-SAM
OGD
Proto-oncogene c-Fgr
soluble FGFR1 variant 1
soluble FGFR1 variant 2
Background
FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for FGFR1 Antibody (MAB658). (Showing 1 - 2 of 2 FAQs).
I would like to inquire whether you have samples of the following antibodies: NBP1-61338, NB600-1287, NBP1-19481, NBP1-19864; The datasheets for these antibodies show different molecular weights of the detected proteins so its no altogether clear to me which one detects the real protein. To sort this out, we would be using FGFR1-deficient cells and would very much appreciate if you could supply us with small aliquots of these antibodies.
FGFR1 has multiple isoforms and is subject to multiple PTM's. The molecular weight can vary greatly depending on experimental conditions and samples used. We fully guarantee all of our products for the listed applications and species. If you cannot get a product to work in an application or species stated on our datasheet, our technical service team will troubleshoot with you to get it to work. If a product still does not work after troubleshooting, you can receive a free of charge replacement product or a full refund. Due to our 100% guarantee, we do not offer free of charge samples of our products. If a smaller sample size is available, it will be listed on our product page.
I am working in Multiple sclerosis group and mainly working with mice model and cell culture study. I need FGFR1 antibody against Mice for FACS analysis. If it is available can I get the sample to check with my cells? And any Oligodendrocyte markers against mice for FACS too.
We do have an antibody that has been tested in FLOW, NB600-1287, however it has not been tested in mouse. If you would like to test this antibody in mouse samples we have an Innovators Reward Program where we reward you for trying our antibody in species and applications that have not been previously tested.
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