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DPYD Antibody (C1)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
C1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

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DPYD Antibody (C1) Summary

Immunogen
Immunized with recombinant Human DPYD (Uniprot#: Q12882; Ile781-Cys1025 (Uniprot#: Q12882)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
DPYD
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 5-20ug/mL
  • Immunohistochemistry 5-20ug/mL
  • Western Blot 0.2-2ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH7.4, 50% glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for DPYD Antibody (C1)

  • DHP
  • DHPDHASE
  • dihydropyrimidine dehydrogenase [NADP+]
  • dihydropyrimidine dehydrogenase
  • Dihydrothymine dehydrogenase
  • Dihydrouracil dehydrogenase
  • DPDMGC132008
  • EC 1.3.1.2
  • MGC70799

Background

DPYD is encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Bioinformatics

Gene Symbol DPYD