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Dopamine D3R/DRD3 Antibody (SR1747)

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Western Blot: Dopamine D3R/DRD3 Antibody (SR1747) [NBP3-21963] - Western blot analysis using NBP3-21963 in SH-SY5Y cell lysate.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
SR1747
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Dopamine D3R/DRD3 Antibody (SR1747) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human Dopamine D3R/DRD3 (Uniprot #: P35462)
Specificity
Detects endogenous levels of total Dopamine D3R/DRD3
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
DRD3
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
Theoretical MW
44 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Dopamine D3R/DRD3 Antibody (SR1747)

  • D(3) dopamine receptor
  • D3DR
  • Dopamine D3 R
  • Dopamine D3 receptor
  • Dopamine D3R
  • dopamine receptor D3
  • DRD3
  • essential tremor 1
  • ETM1
  • FET1
  • MGC149204
  • MGC149205

Background

The DRD3 Dopamine Receptor is expressed in brain regions associated with cognitive, emotional, and endocrine functions. DRD3 mediates the effects of drugs used in the treatment of schizophrenia and Parkinson's disease. DRD3 also binds BP897, a potent inhibitor of drug-craving and cocaine-seeking behaviors. Mutations in DRD3 lead to sodium retention in the kidney, resulting in hypertension and increased locomotor activity in mice. Multiple isoforms of DRD3 are produced by alternative splicing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DRD3