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Dopamine D1R/DRD1 Antibody - BSA Free

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Immunohistochemistry-Paraffin: Dopamine D1 R/DRD1 Antibody [NLS43] - Analysis of anti-Dopamine Receptor D1 / DRD1 antibody with human kidney, tubules at dilution 8 ug/ml.
Immunohistochemistry: Dopamine D1R/DRD1 Antibody - BSA Free [NLS43] - Immunohistochemistry of Brain, Alzheimer's protoplasmic astrocyte

Product Details

Summary
Reactivity Hu, Mu, Po, Bv, Ca, Pm, Pm, Bt, HaSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

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Dopamine D1R/DRD1 Antibody - BSA Free Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 15 amino acid peptide from 3rd cytoplasmic domain of human Dopamine D1R/DRD1.
Epitope
3rd cytoplasmic domain
Localization
Cell membrane; multi pass membrane protein.
Specificity
Human DRD1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Hamster (93%), Bat (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DRD1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 8 ug/ml
Application Notes
.
Control
Human Brain Frontal Lobe Whole Tissue Lysate (Adult Whole Depression)
Dopamine D1R/DRD1 Overexpression Lysate
Publications
Read Publications using
NLS43 in the following applications:

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Rat (87%), Turkey (87%), Chicken (87%), Xenopus (80%). Use in Mouse reported in scientific literature (PMID:32783894).

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Dopamine D1R/DRD1 Antibody - BSA Free

  • D(1A) dopamine receptor
  • D1DR
  • DADR
  • Dopamine D1 R
  • Dopamine D1 receptor
  • Dopamine D1R
  • dopamine receptor D1
  • DRD1
  • DRD1A

Background

DRD1, a Dopamine Receptor, mediates the effect of the neurotransmitter dopamine, an intermediate in the biosynthesis of noradrenaline and adrenaline. It is involved in the control of motor activity and cognitive memory. Downregulation of DRD1 leads to severe impairments in working memory and to locomotor hyperactivity, which are observed in diseases such as schizophrenia, Parkinson's disease, affective disorders, and attention deficit hyperactivity disorder. DRD1 enhances smooth muscle contraction and vasodilation in the heart. It also modulates sodium transport in the kidney and is involved in the pathogenesis of hypertension. Dopamine receptor D1 has been reported mostly in various regions of the brain. ESTs have been isolated from normal olfactory epithelium and cancerous genitourinary tract libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Dopamine D1R/DRD1 Antibody (NLS43)(2)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 2 applications: IF/IHC, IHC-P.


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(1)
IHC-P
(1)
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Product General Protocols

View specific protocols for Dopamine D1R/DRD1 Antibody (NLS43): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Dopamine D1R/DRD1 Antibody (NLS43) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DRD1
Entrez