| Reactivity | Hu, Mu, RtSpecies Glossary |
| Applications | WB, Simple Western |
| Clonality | Polyclonal |
| Host | Goat |
| Conjugate | Unconjugated |
| Concentration | LYOPH |
| Immunogen | E. coli-derived recombinant human DOK7 Ala179-Pro299 Accession # Q18PE1 |
| Specificity | Detects human, mouse, and rat DOK7 in Western blots. |
| Source | N/A |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Goat |
| Gene | DOK7 |
| Purity Statement | Antigen Affinity-purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Publications |
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| Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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| Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
| Preservative | No Preservative |
| Concentration | LYOPH |
| Reconstitution Instructions | Reconstitute at 0.2 mg/mL in sterile PBS. |
DOK7 (Downstream of kinase 7) is a 55 kDa member of the DOK family of cytoplasmic adaptor proteins. It links the acetylcholine receptor and the receptor tyrosine kinase MuSK in skeletal and cardiac muscle. Mutations can cause familial myasthenic syndromes. The 504 amino acid (aa) human DOK7 contains pleckstrin homology (aa 7‑109) and phosphotyrosine-binding (PTK, aa 125‑236) and SH2 domains and a C‑terminal nuclear export signal. Splicing isoforms of 255, 608, and 366 aa diverge at aa 175 or 500, or have 40 divergent aa replacing aa 1‑178, respectively. Within aa 179‑299, human DOK7 shares 92% and 93% aa identity with mouse and rat DOK7, respectively.
![DOK7 Antibody [Unconjugated]](/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png "DOK7 Antibody [Unconjugated]")
Secondary Antibodies |
Isotype Controls |
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