DDIT4 Antibody - BSA Free

RTP801 was initially identified as a gene induced by DNA damage, and later found to also be regulated by other cellular stresses such as hypoxia and glucocorticoid treatment. Recently, RTP801 has been shown to act as a mediator of tuberous sclerosis complex (TSC)-dependent regulation of the mammalian Target of Rapamycin (mTOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle. In response to energy stress, RTP801 inhibits mTOR function, resulting in dephosphorylation of downstream targets such as ribosomal protein S6 kinase 1 and 4EBP1 and decreasing cell growth. Disregulation of RTP801 may thus contribute to human tumorigenesis.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ICC/IF, WB.

Showing Publications 1 - 2 of 2.

Publications using NBP1-77321	Applications	Species
Schwenzer H, Juhling F, Chu A et al. Oxidative Stress Triggers Selective tRNA Retrograde Transport in Human Cells during the Integrated Stress Response Cell Rep 2019-03-19 [PMID: 30893612] (ICC/IF, Human)	ICC/IF	Human
Chen DP, Ma YP, Zhuo L, Zhang Z. 1,25-Dihydroxyvitamin D3inhibits the proliferation of rat mesangial cells induced by high glucose via DDIT4. Oncotarget. 2018-01-02 [PMID: 29416624] (WB, Human)	WB	Human

Array NBP1-77321

• DDIT4 Antibodies
• DDIT4 Lysate
• DDIT4 Proteins