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Cystatin E/M/CST6 Antibody (RM0217-6F49) [mFluor Violet 500 SE]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, B/N
Clone
RM0217-6F49
Clonality
Monoclonal
Host
Rat
Conjugate
mFluor Violet 500 SE

Order Details

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Cystatin E/M/CST6 Antibody (RM0217-6F49) [mFluor Violet 500 SE] Summary

Immunogen
Mouse recombinant Cystatin E/M/CST6
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
CST6
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Block/Neutralize
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Cystatin E/M/CST6 Antibody (RM0217-6F49) [mFluor Violet 500 SE]

  • CST6
  • cystatin 6
  • Cystatin E/M
  • cystatin M
  • cystatin M/E
  • Cystatin-6
  • cystatin-E
  • cystatin-M
  • cysteine proteinase inhibitor

Background

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CST6