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CXCR4 Antibody (247506) [Allophycocyanin/Cy7]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
247506
Clonality
Monoclonal
Host
Rat
Conjugate
Allophycocyanin/Cy7

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB21651U-100UG
Alexa Fluor 405
FAB21651V-100UG
Alexa Fluor 488
FAB21651G-100UG
Alexa Fluor 532
FAB21651X
Alexa Fluor 594
FAB21651T-100UG
Alexa Fluor 647
FAB21651R-100UG
Alexa Fluor 700
FAB21651N-100UG
Alexa Fluor 750
FAB21651S-100UG
Allophycocyanin
FAB21651A-100UG
Allophycocyanin
FAB21651A-025UG
Biotin
FAB21651B
CoraFluor 1
FAB21651CL1
DyLight 350
FAB21651D
DyLight 405
FAB21651E
DyLight 488
FAB21651K
DyLight 550
FAB21651L
DyLight 594
FAB21651M
DyLight 650
FAB21651W
DyLight 680
FAB21651Y
DyLight 755
FAB21651Z
Fluorescein
FAB21651F-100
Fluorescein
FAB21651F-025
HRP
FAB21651H
Janelia Fluor 525
FAB21651JF525
Janelia Fluor 549
FAB21651I
Janelia Fluor 585
FAB21651JF585
Janelia Fluor 635
FAB21651JF635
Janelia Fluor 646
FAB21651J
Janelia Fluor 669
FAB21651JF669
PE/Atto594
FAB21651PEATT594
PE/Cy5.5
FAB21651PECY55
PE/Cy7
FAB21651PECY7
Phycoerythrin
FAB21651P-100
Phycoerythrin
FAB21651P-025
Unconjugated
MAB21651-100
mFluor Violet 450 SE
FAB21651MFV450
mFluor Violet 500 SE
FAB21651MFV500
mFluor Violet 610 SE
FAB21651MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB21651-100
Carrier Free
FAB21651T-100UG
Carrier Free
FAB21651A-100UG
Carrier Free
FAB21651V-100UG
Carrier Free
FAB21651G-100UG
Carrier Free
FAB21651N-100UG
Carrier Free
FAB21651R-100UG
Carrier Free
FAB21651S-100UG
Carrier Free
FAB21651U-100UG
Carrier Free
FAB21651F-025
Carrier Free
MAB21651-500
Carrier Free
MAB21651-SP
Carrier Free
MAB21651-100
Carrier Free
FAB21651P-100
Carrier Free
FAB21651P-025
Carrier Free
FAB21651F-100
Carrier Free
FAB21651A-025UG
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CXCR4 Antibody (247506) [Allophycocyanin/Cy7] Summary

Immunogen
Y3 rat myeloid cell line transfected with mouse CXCR4
Met1-Ser359
Accession # P70658
Specificity
Detects mouse CXCR4 transfectants. Does not stain irrelevant transfectants.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
CXCR4
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for CXCR4 Antibody (247506) [Allophycocyanin/Cy7]

  • CD184
  • chemokine (C-X-C motif) receptor 4
  • chemokine (C-X-C motif), receptor 4 (fusin)
  • C-X-C chemokine receptor type 4
  • CXCR4
  • CXC-R4
  • CXCR-4
  • D2S201E
  • D2S201ESDF-1 receptor
  • FB22
  • Fusin
  • HM89
  • HM89NPYRL
  • HSY3RR
  • LAP3
  • LAP-3
  • LCR1
  • LESTR
  • LESTRCD184 antigen
  • Leukocyte-derived seven transmembrane domain receptor
  • leukocyte-derived seven-transmembrane-domain receptor
  • lipopolysaccharide-associated protein 3
  • neuropeptide Y receptor Y3
  • NPY3R
  • NPY3RWHIM
  • NPYR
  • NPYRL
  • NPYY3R
  • pCXCR4
  • seven transmembrane helix receptor
  • seven-transmembrane-segment receptor, spleen
  • Stromal cell-derived factor 1 receptor
  • WHIMS

Background

CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lympho- and myelopoiesis, cardiogenesis, blood vessel formation and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2. The 12G5 antibody has been reported to block CD4-independent infection by HIV-2 and CD4-dependent infection by some T cell-tropic isolates of HIV-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CXCR4 Antibody
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FAB21651APCCY7
CXCR4 Antibody (247506) [Allophycocyanin/Cy7]
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Product General Protocols

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FAQs for CXCR4 Antibody (FAB21651APCCY7). (Showing 1 - 1 of 1 FAQ).

  1. Which is your best CXCR4 for immunohistochemistry in paraffin tissues? I would like to detect it in paraffin embedded tissues from human breast cancer samples.
    • CXCR4 antibody (NB100-74396) is our best selling product among all the CXCR4 antibodies and it has been validated for IHC-P in human cervical carcinoma tissue sections. NB100-74396 has been cited in at least 7 research publications. Additionally, here is a list of all of our CXCR4 antibodies that has been verified in IHC-P in human samples.

Secondary Antibodies

 

Isotype Controls

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Stemness is responsible for onset and metastasis of colorectal cancer
By Jamshed Arslan, Pharm. D., PhD. Colorectal cancer stem cells are a rare subpopulation of colorectal cancer cells that can self-renew and initiate and sustain tumor growth when transplanted into an animal host.1,2 C...  Read full blog post.
LAMP2: Protector of the lysosome
LAMP2 belongs to the family of membrane glycoproteins who confer selectins with carbohydrate ligands. LAMP2 has been implicated in tumor cell metastasis, as well as overall protection, maintenance, and adhesion of the lysosome. It appears that LAMP2 m...  Read full blog post.
CXCR4 Studies on Neural and Stem Cells
The CXCR4 (C-X-C chemokine receptor type 4) protein is one member of the G-protein coupled receptor (GPCR1) family. As a multipass membrane protein that is found in several tissues, it is the receptor for the C-X-C chemokine CXCL12/SDF-1. The CXCR4 li...  Read full blog post.
Understanding CXCR4 and SDF1
CXCR4 (C-X-C chemokine receptor type 4) is a member of the G-protein coupled receptor (GPCR1) family. It is expressed as a multipass membrane protein in several tissues where it acts as the receptor for the C-X-C chemokine CXCL12/SDF-1. This ligand in...  Read full blog post.
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Bioinformatics

Gene Symbol CXCR4