Home » CXCR4 » CXCR4 Antibodies » CXCR4 Antibody (12G5) [Allophycocyanin]
Novus Biologicals products are now on bio-techne.com

CXCR4 Antibody (12G5) [Allophycocyanin]

 (7 Publications)
 See All Related
Submit a Review

Images

 
(
Enlarge)
Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR4 APC-conjugated Monoclonal Antibody (Catalog # FAB170A) and Mouse Anti-Human CD19 PE-conjugated Monoclonal Antibody (Catalog # FAB4867P). View our protocol for Staining Membrane-associated Proteins.
Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR4 APC-conjugated Monoclonal Antibody (Catalog # FAB170A) and Mouse Anti-Human CD19 PE-conjugated Monoclonal Antibody (Catalog # FAB4867P). View ...read more
Jurkat (filled histogram) vs K562 (open histogram) cells were stained with Mouse Anti-Human CXCR4 APC‑conjugated Monoclonal Antibody (Catalog # FAB170A). View our protocol for Staining Membrane-associated ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
12G5
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB170U-100UG
Alexa Fluor 405
FAB170V-100UG
Alexa Fluor 488
FAB170G-025
Alexa Fluor 488
FAB170G-100
Alexa Fluor 532
FAB170X
Alexa Fluor 594
FAB170T-100UG
Alexa Fluor 647
FAB170R-100UG
Alexa Fluor 750
FAB170S-100UG
Allophycocyanin
FAB170A-100
Allophycocyanin/Cy7
FAB170APCCY7
Biotin
FAB170B
DyLight 350
FAB170D
DyLight 405
FAB170E
DyLight 488
FAB170K
DyLight 550
FAB170L
DyLight 594
FAB170M
DyLight 650
FAB170W
DyLight 680
FAB170Y
DyLight 755
FAB170Z
Fluorescein
FAB170F-025
Fluorescein
FAB170F-100
HRP
FAB170H
Janelia Fluor 549
FAB170I
Janelia Fluor 646
FAB170J
PE/Atto594
FAB170PEATT594
PE/Cy5.5
FAB170PECY55
PE/Cy7
FAB170PECY7
Phycoerythrin
FAB170P-100
Phycoerythrin
FAB170P-025
Unconjugated
MAB170
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB170
Carrier Free
FAB170G-025
Carrier Free
FAB170S-100UG
Carrier Free
FAB170T-100UG
Carrier Free
FAB170U-100UG
Carrier Free
FAB170V-100UG
Carrier Free
MAB170-SP
Carrier Free
MAB170
Carrier Free
FAB170G-100
Carrier Free
FAB170F-025
Carrier Free
FAB170B
Carrier Free
FAB170A-100
Carrier Free
FAB170P-100
Carrier Free
FAB170P-025
Carrier Free
FAB170F-100
Carrier Free
FAB170R-100UG
Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Novus Biologicals, part of Bio-Techne, offers 100% Guarantee

CXCR4 Antibody (12G5) [Allophycocyanin] Summary

Immunogen
CP-MAC-infected SUP-T1 human T cell lymphoblastic lymphoma line
Accession # P61073
Specificity
Detects human CXCR4.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CXCR4
Purity Statement
Protein A or G purified from ascites
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB170A in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CXCR4 Antibody (12G5) [Allophycocyanin]

  • CD184
  • chemokine (C-X-C motif) receptor 4
  • chemokine (C-X-C motif), receptor 4 (fusin)
  • C-X-C chemokine receptor type 4
  • CXCR4
  • CXC-R4
  • CXCR-4
  • D2S201E
  • D2S201ESDF-1 receptor
  • FB22
  • Fusin
  • HM89
  • HM89NPYRL
  • HSY3RR
  • LAP3
  • LAP-3
  • LCR1
  • LESTR
  • LESTRCD184 antigen
  • Leukocyte-derived seven transmembrane domain receptor
  • leukocyte-derived seven-transmembrane-domain receptor
  • lipopolysaccharide-associated protein 3
  • neuropeptide Y receptor Y3
  • NPY3R
  • NPY3RWHIM
  • NPYR
  • NPYRL
  • NPYY3R
  • pCXCR4
  • seven transmembrane helix receptor
  • seven-transmembrane-segment receptor, spleen
  • Stromal cell-derived factor 1 receptor
  • WHIMS

Background

CXCR4, also known as CD184, is a G-protein-linked seven transmembrane spanning receptor that binds stromal cell-derived factor-1 (SDF-1). CXCR4 acts as a co-factor for T-cell tropic HIV-1 and -2 viral entry into cells.

  1. Endres, M.J. et al. (1996) Cell 87:745.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

CXCL12/SDF-1 alpha
[Unconjugated]
350-NS
SDS-PAGE CXCL12/SDF-1 alpha [Unconjugated]
Bioactivity CXCL12/SDF-1 alpha [Unconjugated]
(188 Publications)
Species: Fe, Hu, RM
Applications: BA, BA
CCR5 Antibody
(45531) [Unconjugated
MAB182
Flow Cytometry CCR5 Antibody (45531) [Unconjugated]
Neutralization CCR5 Antibody (45531) [Unconjugated]
Immunocytochemistry CCR5 Antibody (45531) [Unconjugated]
(1 Review)
(32 Publications)
Species: Hu
Applications: CyTOF-ready, Flow, ICC, Neut
CD4 Antibody - BSA
Free
NBP1-19371
Immunohistochemistry-Frozen CD4 Antibody - BSA Free
Immunohistochemistry-Paraffin CD4 Antibody - BSA Free
Flow Cytometry CD4 Antibody - BSA Free
(9 Reviews)
(50 Publications)
Species: Ca, Hu, Mu, Po, Rb, Rt
Applications: Dual ISH-IHC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB
CD34 Antibody
[Unconjugated]
AF4117
Immunohistochemistry CD34 Antibody [Unconjugated]
(3 Reviews)
(37 Publications)
Species: Rt
Applications: IHC, WB
VEGF [HRP]
DVE00
N/A VEGF [HRP]
N/A VEGF [HRP]
N/A VEGF [HRP]
(683 Publications)
Species: Hu
Applications: ELISA
CCL5/RANTES [HRP]
DRN00B
N/A CCL5/RANTES [HRP]
N/A CCL5/RANTES [HRP]
N/A CCL5/RANTES [HRP]
(100 Publications)
Species: Hu
Applications: ELISA
CCR3 Antibody
(61828)
MAB155
Immunohistochemistry CCR3 Antibody (61828)
Neutralization CCR3 Antibody (61828)
(20 Publications)
Species: Hu
Applications: CyTOF-ready, Flow, IHC, Neut
CCR7 Antibody
(150503) [Unconjugate
MAB197
Immunocytochemistry CCR7 Antibody (150503) [Unconjugated]
Immunohistochemistry CCR7 Antibody (150503) [Unconjugated]
Neutralization CCR7 Antibody (150503) [Unconjugated]
(1 Review)
(103 Publications)
Species: Hu
Applications: CyTOF-reported, Dual ISH-IHC, Flow, ICC, IHC, Neut
ERK1 Antibody
(1E5) - BSA Free
NBP2-22203
Flow Cytometry ERK1 Antibody (1E5) - BSA Free
Immunocytochemistry/ Immunofluorescence ERK1 Antibody (1E5) - BSA Free
Immunohistochemistry-Paraffin ERK1 Antibody (1E5) - BSA Free
(1 Publication)
Species: Hu, Pm, Mu, Rt
Applications: ELISA, Flow, ICC/IF, IHC, IHC-P, WB
TNF-alpha
[Unconjugated]
210-TA
SDS-PAGE TNF-alpha [Unconjugated]
Bioactivity TNF-alpha [Unconjugated]
SEC-MALS TNF-alpha [Unconjugated]
(3 Reviews)
(811 Publications)
Species: Hu
Applications: BA
CTLA-4
[Unconjugated]
7268-CT
Bioactivity CTLA-4 [Unconjugated]
(3 Publications)
Species: Hu
Applications: BA
ERK2 Antibody
[Unconjugated]
AF1230
Western Blot ERK2 Antibody [Unconjugated]
Immunohistochemistry ERK2 Antibody [Unconjugated]
Knockout Validated ERK2 Antibody [Unconjugated]
(3 Publications)
Species: Hu, Mu, Rt
Applications: IHC, KO, WB
AKT [p Ser473]
Antibody [Unconjugate ...
AF887
Western Blot AKT [p Ser473] Antibody [Unconjugated] - Pan Specific
Simple Western AKT [p Ser473] Antibody [Unconjugated] - Pan Specific
Intracellular Staining by Flow Cytometry AKT [p Ser473] Antibody [Unconjugated] - Pan Specific
(49 Publications)
Species: Hu, Mu, Rt
Applications: CyTOF-ready, IHC, ICFlow, Simple Western, WB
CXCR7/RDC-1
Antibody (11G8) [Unco ...
MAB42273
Immunohistochemistry CXCR7/RDC-1 Antibody (11G8) [Unconjugated]
Flow Cytometry CXCR7/RDC-1 Antibody (11G8) [Unconjugated]
Functional CXCR7/RDC-1 Antibody (11G8) [Unconjugated]
(2 Reviews)
(36 Publications)
Species: Hu
Applications: CyTOF-ready, Flow, IHC
HLA DQ/DR/DP
Antibody (HLA-Pan/296 ...
NBP2-79843
Protein Array HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free
Immunocytochemistry/ Immunofluorescence HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free
Western Blot HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free
Species: Hu
Applications: CyTOF-ready, ELISA, Flow, ICC/IF, IHC, IHC-P, PA, WB
NOD2 Antibody
(2D9) - BSA Free
NB100-524
Flow Cytometry NOD2 Antibody (2D9) - BSA Free
Flow Cytometry NOD2 Antibody (2D9) - BSA Free
Immunohistochemistry-Frozen NOD2 Antibody (2D9) - BSA Free
(1 Review)
(26 Publications)
Species: Hu, Mu
Applications: Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
CXCR3 Antibody
(49801) [Unconjugated
MAB160
Flow Cytometry CXCR3 Antibody (49801) [Unconjugated]
Flow Cytometry CXCR3 Antibody (49801) [Unconjugated]
Neutralization CXCR3 Antibody (49801) [Unconjugated]
(71 Publications)
Species: Hu
Applications: CyTOF-ready, Flow, IHC, Neut
CCR1 Antibody
(53504) [Unconjugated
MAB145
Flow Cytometry CCR1 Antibody (53504) [Unconjugated]
(1 Review)
(26 Publications)
Species: Hu
Applications: CyTOF-ready, Flow
CCL2/JE/MCP-1 [HRP]
DCP00
N/A CCL2/JE/MCP-1 [HRP]
N/A CCL2/JE/MCP-1 [HRP]
N/A CCL2/JE/MCP-1 [HRP]
(255 Publications)
Species: Hu
Applications: ELISA
CXCR4 Antibody
(12G5) [Allophycocyan
FAB170A
CXCR4 Antibody (12G5) [Allophycocyanin]
Species: Hu
Applications: Flow

Publications for CXCR4 Antibody (FAB170A)(7)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(6)
All Applications
Filter By Species
Human
(6)
All Species
Showing Publications 1 - 7 of 7.
Publications using FAB170A Applications Species
Maxwell S. DeNies, Alan V. Smrcka, Santiago Schnell, Allen P. Liu beta -arrestin mediates communication between plasma membrane and intracellular GPCRs to regulate signaling Communications Biology 12/18/2020 [PMID: 33339901]
K Lee, H Cho, RW Rickert, QV Li, J Pulecio, CS Leslie, D Huangfu FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation Cell Rep, 2019-07-09;28(2):382-393.e7. 2019-07-09 [PMID: 31291575] (Flow Cytometry, Human) Flow Cytometry Human
F Gebauer, D Wicklein, M Tachezy, T Grob, D Steinemann, G Manukjan, G Göhring, B Schlegelbe, H Maar, JR Izbicki, M Bockhorn, U Schumacher Establishment and Characterization of a Pair of Patient-derived Human Non-small Cell Lung Cancer Cell Lines from a Primary Tumor and Corresponding Lymph Node Metastasis Anticancer Res, 2016-04-01;36(4):1507-18. 2016-04-01 [PMID: 27069126] (Flow Cytometry, Human) Flow Cytometry Human
Klimatcheva E, Pandina T, Reilly C, Torno S, Bussler H, Scrivens M, Jonason A, Mallow C, Doherty M, Paris M, Smith E, Zauderer M CXCL13 antibody for the treatment of autoimmune disorders. BMC Immunol, 2015-02-12;16(0):6. 2015-02-12 [PMID: 25879435] (Flow Cytometry, Human) Flow Cytometry Human
Takahashi K, Tanabe K, Ohnuki M, Narita M, Sasaki A, Yamamoto M, Nakamura M, Sutou K, Osafune K, Yamanaka S Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm. Nat Commun, 2014-04-24;5(0):3678. 2014-04-24 [PMID: 24759836] (Flow Cytometry, Human) Flow Cytometry Human
Goldman O, Han S, Sourisseau M, Dziedzic N, Hamou W, Corneo B, D'Souza S, Sato T, Kotton D, Bissig K, Kalir T, Jacobs A, Evans T, Evans M, Gouon-Evans V KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development. Cell Stem Cell, 2013-06-06;12(6):748-60. 2013-06-06 [PMID: 23746980] (Flow Cytometry, Human) Flow Cytometry Human
Ahern D, Lloyd CM, Robinson DS Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors. Allergy, 2009-02-07;64(8):1121-9. 2009-02-07 [PMID: 19208087] (Flow Cytometry, Human) Flow Cytometry Human

Reviews for CXCR4 Antibody (FAB170A) (0)

There are no reviews for CXCR4 Antibody (FAB170A). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for CXCR4 Antibody (FAB170A). (Showing 1 - 1 of 1 FAQs).

  1. Which is your best CXCR4 for immunohistochemistry in paraffin tissues? I would like to detect it in paraffin embedded tissues from human breast cancer samples.
    • CXCR4 antibody (NB100-74396) is our best selling product among all the CXCR4 antibodies and it has been validated for IHC-P in human cervical carcinoma tissue sections. NB100-74396 has been cited in at least 7 research publications. Additionally, here is a list of all of our CXCR4 antibodies that has been verified in IHC-P in human samples.

Secondary Antibodies

 

Isotype Controls

Additional CXCR4 Products

Blogs on CXCR4.

Check out the latest blog posts on CXCR4.
Stemness is responsible for onset and metastasis of colorectal cancer
By Jamshed Arslan, Pharm. D., PhD. Colorectal cancer stem cells are a rare subpopulation of colorectal cancer cells that can self-renew and initiate and sustain tumor growth when transplanted into an animal host.1,2 C...  Read full blog post.
LAMP2: Protector of the lysosome
LAMP2 belongs to the family of membrane glycoproteins who confer selectins with carbohydrate ligands. LAMP2 has been implicated in tumor cell metastasis, as well as overall protection, maintenance, and adhesion of the lysosome. It appears that LAMP2 m...  Read full blog post.
CXCR4 Studies on Neural and Stem Cells
The CXCR4 (C-X-C chemokine receptor type 4) protein is one member of the G-protein coupled receptor (GPCR1) family. As a multipass membrane protein that is found in several tissues, it is the receptor for the C-X-C chemokine CXCL12/SDF-1. The CXCR4 li...  Read full blog post.
Understanding CXCR4 and SDF1
CXCR4 (C-X-C chemokine receptor type 4) is a member of the G-protein coupled receptor (GPCR1) family. It is expressed as a multipass membrane protein in several tissues where it acts as the receptor for the C-X-C chemokine CXCL12/SDF-1. This ligand in...  Read full blog post.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR4 PE-conjugated Monoclonal Antibody (Catalog # FAB170P) and Mouse Anti-Human CD19 APC-conjugated Monoclonal Antibody (FAB4867A) for 15 minutes at 37°C followed by 15 minutes at room temperature. View our protocol for Staining Membrane-associated Proteins.
CXCR4 Antibody (12G5) [Phycoerythrin]
FAB170P-025
1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.
TNF-alpha [Unconjugated]
210-TA-005

Contact Information

Product PDFs

  PDF SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our CXCR4 Antibody (12G5) [Allophycocyanin] and receive a gift card or discount.


Bioinformatics

Gene Symbol CXCR4
Uniprot