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CSB Antibody [Alexa Fluor® 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Alexa Fluor 488

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CSB Antibody [Alexa Fluor® 488] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1161 and 1211 of human Cockayne syndrome protein B (excision repair cross-complementing rodent repair deficiency, complementation group 6) using the numbering given in entry NP_000115.1 (GeneID 2074).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ERCC6
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CSB Antibody [Alexa Fluor® 488]

  • ARMD5
  • ATP-dependent helicase ERCC6
  • CKN2
  • Cockayne syndrome group B protein
  • Cockayne syndrome protein CSB
  • COFS
  • COFS1
  • CSBCockayne syndrome B protein
  • DNA excision repair protein ERCC-6
  • EC 3.6.1
  • EC 3.6.4.-
  • excision repair cross-complementing rodent repair deficiency, complementationgroup 6
  • Rad26 homolog
  • RAD26

Background

ERCC6, also known as Cockayne syndrome B protein, is involved in DNA repair in response to UV exposure. ERCC6 has been reported to display ATPase and helicase activity and functions as a transcriptional regulator. Mutations in ERCC6 are the cause of Cockayne syndrome type B (CSB), cerebro-oculo-facio-skeletal syndrome type 1 (COFS1), De Sanctis-Cacchione syndrome (DCS), age-related macular degeneration type 5 (ARMD5), and UV-sensitive syndrome (UVS).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Array NB100-61070AF488

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Bioinformatics

Gene Symbol ERCC6
Entrez
Uniprot