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CRIPTO Antibody (89633) [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications Flow, B/N, CyTOF-ready, ELISA, ELISA(Cap), ELISA(Det), ICC/IF
Clone
89633
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 610 SE

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CRIPTO Antibody (89633) [mFluor Violet 610 SE] Summary

Immunogen
E. coli-derived recombinant human Cripto-1
Arg38-Tyr188
Accession # P13385
Specificity
Detects human and primate Cripto-1 in ELISAs. In sandwich immunoassays, no cross-reactivity with recombinant mouse Cripto-1, recombinant human (rh) EGF, rhTGF‑ alpha , rhTGF-beta 1, rhTGF-beta 2, rhTGF-beta 3, or rhCryptic is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TDGF1
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Blockade of Receptor-ligand Interaction
  • CyTOF-ready
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Flow Cytometry
  • Immunocytochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CRIPTO Antibody (89633) [mFluor Violet 610 SE]

  • CFC-2
  • CR
  • Cripto
  • Cripto-1 growth factor
  • Cripto-1
  • CRIPTOCRGF
  • Epidermal growth factor-like cripto protein CR1
  • TDGF1
  • TDGF-1
  • teratocarcinoma-derived growth factor 1

Background

Teratocarcinoma-derived growth factor 1 (TDGF1), also known as CRIPTO, is expressed both in ES cells and during the early phases of embryo development. During development, CRIPTO is thought to play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. In adults, it is reactivated in a wide range of epithelial cancers.

CRIPTO-1 antibodies are useful tools for studying embryonic development and certian cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TDGF1