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Cbx2 Antibody (RAB-C238) [Alexa Fluor® 532] - Chimeric

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, ICC/IF, IP, ChIP, MS
Clone
RAB-C238
Clonality
Monoclonal
Host
Rabbit
Conjugate
Alexa Fluor 532

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Cbx2 Antibody (RAB-C238) [Alexa Fluor® 532] - Chimeric Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained by recombinant antibody (rAb) phage display recognizing CBX2 protein under non-denaturing conditions.
Epitope
This antibody binds to a folded domain, amino acids 2-70.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
CBX2
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Chromatin Immunoprecipitation (ChIP)
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Mass Spectrometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Cbx2 Antibody (RAB-C238) [Alexa Fluor® 532] - Chimeric

  • Cbx2
  • CDCA6
  • cell division cycle associated 6
  • chromobox homolog 2 (Drosophila Pc class)
  • chromobox homolog 2 (Pc class homolog, Drosophila)
  • chromobox homolog 2
  • chromobox protein homolog 2
  • M33
  • MGC10561
  • modifier 3
  • Pc class homolog
  • SRXY5

Background

Polycomb' genes in Drosophila maintain the repressed state of homeotic and other developmentally regulatedgenes (Wedeen et al., 1986 (PubMed 3081265); Kuziora and McGinnis, 1988 (PubMed 2903050)) by mediating changes inhigher-order chromatin structure (Paro and Hogness, 1991 (PubMed 1898775)). M33, a mouse homolog of polycomb, wasisolated by means of the structural similarity of its chromodomain (Pearce et al., 1992 (PubMed 1352241)). The fifthexon of M33 contains a region of homology shared by Drosophila and Xenopus. In Drosophila, its deletion results in theloss of polycomb function.(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Array NBP3-20135AF532

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Bioinformatics

Gene Symbol CBX2