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CARD11/CARMA1 Antibody [DyLight 680]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 680

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CARD11/CARMA1 Antibody [DyLight 680] Summary

Immunogen
Antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human CARMA1. The immunogen is located within the last 50 amino acids of CARMA1. Amino Acid Squence: EEQRKTIWVDEDQL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CARD11
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CARD11/CARMA1 Antibody [DyLight 680]

  • BIMP3
  • BIMP3card-maguk protein 1
  • CARD11
  • CARD-containing MAGUK protein 1
  • Carma 1
  • CARMA1
  • CARMA1bcl10-interacting maguk protein 3
  • caspase recruitment domain family, member 11
  • caspase recruitment domain-containing protein 11
  • MGC133069

Background

CARD11 belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CARD11/CARMA1 Antibody (NBP1-77219FR) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CARD11