Western Blot: Carboxypeptidase M Antibody [NBP1-87403] - Analysis in human cell line THP-1.
Immunohistochemistry-Paraffin: Carboxypeptidase M Antibody [NBP1-87403] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: Carboxypeptidase M Antibody [NBP1-87403] - Staining of human endometrium shows strong positivity in apical membrane in glandular cells.
Immunohistochemistry-Paraffin: Carboxypeptidase M Antibody [NBP1-87403] - Staining of human kidney shows weak membranous/ secretion positivity in cells in glomeruli.
Immunohistochemistry-Paraffin: Carboxypeptidase M Antibody [NBP1-87403] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
This antibody was developed against Recombinant Protein corresponding to amino acids: LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CPM
Purity
Immunogen affinity purified
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Immunogen displays the following percentage of sequence identity for non-tested species: Rat (88%). Use in Mouse reported in scientific literature (PMID:31401267).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for Carboxypeptidase M Antibody
Carboxypeptidase M
CPM
EC 3.4.17
EC 3.4.17.12
Background
The protein encoded by the Carboxypeptidase M gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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