Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Canine IL-8/CXCL8 DuoSet ELISA, 15 Plate
3-10C
AMCF-I
C-X-C motif chemokine 8
CXCL8
CXCL8SCYB8
Emoctakin
GCP1
GCP-1TSG-1
IL8
IL-8
interleukin 8
K60
LAI
LECT
LUCT
LYNAP
MDNCF
MDNCFb-ENAP
member 8
MONAP
MONAPGCP1
NAF
NAP1
NAP-1NAP1
NCF
Neutrophil-activating protein 1
Protein 3-10C
T cell chemotactic factor
T-cell chemotactic factor
TCF
TSG1
Background
Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.