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Beta Ig-h3/TGFBI Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: Beta Ig-h3/TGFBI Antibody [NBP2-48534] - Analysis in human placenta and pancreas tissues using NBP2-48534 antibody. Corresponding TGFBI RNA-seq data are ...read more
Independent Antibodies: Immunohistochemistry-Paraffin: Beta Ig-h3/TGFBI Antibody [NBP2-48534] - Staining of human gastrointestinal, pancreas, placenta and skin using Anti-Beta Ig-h3/TGFBI antibody NBP2-48534 (A) ...read more
Western Blot: Beta Ig-h3/TGFBI Antibody [NBP2-48534] - Analysis in human plasma.
Immunohistochemistry-Paraffin: Beta Ig-h3/TGFBI Antibody [NBP2-48534] - Staining of human eye shows moderate extracellular positivity in cornea.
Immunohistochemistry-Paraffin: Beta Ig-h3/TGFBI Antibody [NBP2-48534] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry: Beta Ig-h3/TGFBI Antibody [NBP2-48534] - Staining of human placenta shows moderate positivity in extracellular matrix of trophoblastic cells.
Immunohistochemistry-Paraffin: Beta Ig-h3/TGFBI Antibody [NBP2-48534] - Staining of human rectum shows moderate positivity in extracellular matrix of glandular cells.
Immunohistochemistry-Paraffin: Beta Ig-h3/TGFBI Antibody [NBP2-48534] - Staining of human skin shows moderate positivity in extracellular matrix in dermis.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Beta Ig-h3/TGFBI Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: NREGVYTVFAPTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSLKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSALEIFKQAS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TGFBI
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Beta Ig-h3/TGFBI Recombinant Protein Antigen (NBP2-48534PEP)

Reactivity Notes

Mouse (88%), Rat (87%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Beta Ig-h3/TGFBI Antibody

  • beta IGH3
  • beta IG-H3
  • BIGH3EBMD
  • CDB1
  • CDG2
  • CDGG1transforming growth factor, beta-induced, 68kD
  • CSD
  • CSD1
  • CSD2
  • CSD3
  • Kerato-epithelin
  • LCD1
  • RGD-CAP
  • RGD-containing collagen-associated protein
  • TGFBI
  • TGFBIP
  • transforming growth factor, beta-induced, 68kDa
  • transforming growth factor-beta-induced protein ig-h3

Background

TGFBI encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TGFBI