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Bcl-10 Antibody (SPM520) [mFluor Violet 450 SE]

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Bcl-10 Antibody (SPM520) [mFluor Violet 450 SE] [NBP2-34415MFV450] - Vial of mFluor Violet 450 conjugated antibody. mFluor Violet 450 is optimally excited at 406 nm by the Violet laser (405 nm) and has an emission maximum of 445 nm.
Bcl-10 Antibody (SPM520) [mFluor Violet 450 SE] [NBP2-34415MFV450] - Vial of mFluor Violet 450 conjugated antibody. mFluor Violet 450 is optimally excited at 406 nm by the Violet laser (405 nm) and has an emission ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, CyTOF-ready
Clone
SPM520
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 450 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-34415AF350
Alexa Fluor 405
NBP2-34415AF405
Alexa Fluor 488
NBP2-34415AF488
Alexa Fluor 532
NBP2-34415AF532
Alexa Fluor 594
NBP2-34415AF594
Alexa Fluor 647
NBP2-34415AF647
Alexa Fluor 700
NBP2-34415AF700
Alexa Fluor 750
NBP2-34415AF750
Allophycocyanin
NBP2-34415APC
Biotin
NBP2-34415B
CoraFluor 1
NBP2-34415CL1
DyLight 350
NBP2-34415UV
DyLight 405
NBP2-34415V
DyLight 488
NBP2-34415G
DyLight 550
NBP2-34415R
DyLight 594
NBP2-34415DL594
DyLight 650
NBP2-34415C
DyLight 680
NBP2-34415FR
DyLight 755
NBP2-34415IR
FITC
NBP2-34415F
HRP
NBP2-34415H
Janelia Fluor 525
NBP2-34415JF525
Janelia Fluor 549
NBP2-34415JF549
Janelia Fluor 585
NBP2-34415JF585
Janelia Fluor 635
NBP2-34415JF635
Janelia Fluor 646
NBP2-34415JF646
Janelia Fluor 669
NBP2-34415JF669
PE
NBP2-34415PE
PerCP
NBP2-34415PCP
Unconjugated
NBP2-34368-0.1mg
mFluor Violet 500 SE
NBP2-34415MFV500
mFluor Violet 610 SE
NBP2-34415MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-34368-0.1mg
IHC-Prediluted
NBP2-45153
Azide and BSA Free
NBP2-34415-0.1mg
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Bcl-10 Antibody (SPM520) [mFluor Violet 450 SE] Summary

Immunogen
Human Bcl-10 recombinant protein (epitope aa122-168) (Uniprot: O95999)
Specificity
This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
BCL10
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Bcl-10 Antibody (SPM520) [mFluor Violet 450 SE]

  • B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10
  • Bcl10
  • Bcl-10
  • CARD-containing apoptotic signaling protein
  • CARD-containing molecule enhancing NF-kappa-B
  • CARD-containing proapoptotic protein
  • CARD-like apoptotic protein
  • CARMEN
  • caspase-recruiting domain-containing protein
  • cCARMEN
  • c-E10
  • c-E10bcl-10
  • CED-3/ICH-1 prodomain homologous E10-like regulator
  • Cellular homolog of vCARMEN
  • cellular-E10
  • CIPER
  • CLAP
  • hCLAP
  • Mammalian CARD-containing adapter molecule E10
  • mE10
  • mE10CARD containing molecule enhancing NF-kB

Background

Bcl-10 is an adaptor protein with a caspase recruitment domain (CARD) that promotes apoptosis and activates pro-caspase 9 and NF-kB (1-2). Bcl-10 also interacts with other CARD domain containing proteins including CARD9, 10, 11 and 14. Bcl-10 is found to form a complex with MALT1, a protein known to be translocated in MALT lymphomas. Bcl-10 and MALT1 play a critical role in antigen receptor

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol BCL10