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ATG7 Antibody (683906) [FITC]

 
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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Simple Western, IHC, CyTOF-ready, Flow, ICC/IF
Clone
683906
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB6608U-100UG
Alexa Fluor 405
FAB6608V-100UG
Alexa Fluor 488
FAB6608G-100UG
Alexa Fluor 532
FAB6608X
Alexa Fluor 594
FAB6608T-100UG
Alexa Fluor 647
IC6608R-100UG
Alexa Fluor 647
FAB6608R-100UG
Alexa Fluor 700
FAB6608N-100UG
Alexa Fluor 750
FAB6608S-100UG
Allophycocyanin
FAB6608A
Biotin
FAB6608B
CoraFluor 1
FAB6608CL1
DyLight 350
FAB6608D
DyLight 405
FAB6608E
DyLight 488
FAB6608K
DyLight 550
FAB6608L
DyLight 594
FAB6608M
DyLight 650
FAB6608W
DyLight 680
FAB6608Y
DyLight 755
FAB6608Z
HRP
FAB6608H
Janelia Fluor 525
FAB6608JF525
Janelia Fluor 549
FAB6608I
Janelia Fluor 585
FAB6608JF585
Janelia Fluor 635
FAB6608JF635
Janelia Fluor 646
FAB6608J
Janelia Fluor 669
FAB6608JF669
PE
FAB6608P
PerCP
FAB6608C
Unconjugated
MAB6608
mFluor Violet 450 SE
FAB6608MFV450
mFluor Violet 500 SE
FAB6608MFV500
mFluor Violet 610 SE
FAB6608MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB6608
Carrier Free
IC6608R-100UG
Carrier Free
MAB6608
Carrier Free
MAB6608-SP
Carrier Free
FAB6608V-100UG
Carrier Free
FAB6608U-100UG
Carrier Free
FAB6608T-100UG
Carrier Free
FAB6608S-100UG
Carrier Free
FAB6608R-100UG
Carrier Free
FAB6608N-100UG
Carrier Free
FAB6608G-100UG
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ATG7 Antibody (683906) [FITC] Summary

Immunogen
E. coli-derived recombinant human ATG7
Asn387-Gln570
Accession # O95352
Specificity
Detects human ATG7 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human ATG3, 4A, 4B, 5, 10, 12, or 16L1 is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ATG7
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Immunocytochemistry
  • Immunohistochemistry
  • Intracellular Staining by Flow Cytometry
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for ATG7 Antibody (683906) [FITC]

  • APG7 autophagy 7-like (S. cerevisiae)
  • APG7
  • APG7L
  • APG7-LIKE
  • ATG12-activating enzyme E1 ATG7
  • ATG7 autophagy related 7 homolog (S. cerevisiae)
  • ATG7
  • Autophagy-related protein 7
  • DKFZp434N0735
  • GSA7
  • hAGP7
  • ubiquitin activating enzyme E1-like protein
  • Ubiquitin-activating enzyme E1-like protein
  • ubiquitin-like modifier-activating enzyme ATG7

Background

FUNCTION: Functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. Forms intermediate conjugates with GABARAPL1 (GABARAPL2, GABARAP or MAP1ALC3). Formation of the final GABARAPL1-PE conjugate is essential for autophagy. SUBUNIT: Homodimer (By similarity). Interacts with ATG3 and ATG12. The complex, composed of ATG3 and ATG7, plays a role in the conjugation of ATG12 to ATG5. SUBCELLULAR LOCATION: Cytoplasm (Probable). ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. TISSUE SPECIFICITY: Widely expressed, especially in kidney, liver, lymph nodes and bone marrow. DOMAIN: The C-terminal part of the protein is essential for the dimerization and interaction with ATG3 and ATG12. SIMILARITY: Belongs to the ATG7 family.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAB6608F
ATG7 Antibody (683906) [FITC]
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Bioinformatics

Gene Symbol ATG7