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AGPAT6 Antibody

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Immunohistochemistry-Paraffin: AGPAT6 Antibody [NBP1-85061] - Staining of human adrenal gland shows cytoplasmic positivity in glandular cells.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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AGPAT6 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: FAWATLRMERGAKEKNHQLYKPYTNGIIAKDPTSLEEEIKEIRRSGSSKALDNTPEFELSDIFYFCRKGMETIMDDEVTKRFSAEELESW
Predicted Species
Mouse (98%), Rat (98%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AGPAT6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
AGPAT6 Protein (NBP1-85061PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for AGPAT6 Antibody

  • 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acidacyltransferase, zeta)
  • Acyl-CoA:glycerol-3-phosphate acyltransferase 4
  • DKFZp586M1819,1-acyl-sn-glycerol-3-phosphate acyltransferase zeta
  • EC 2.3.1.15
  • glycerol-3-phosphate acyltransferase 4,1-AGP acyltransferase 6
  • glycerol-3-phosphate acyltransferase 6,1-AGPAT 6
  • GPAT4,1-acylglycerol-3-phosphate O-acyltransferase 6
  • LPAAT-zetaLPAATZ
  • Lysophosphatidic acid acyltransferase zeta
  • testis spermatogenesis apoptosis-related protein 7
  • TSARG7

Background

Glycerol-3-phosphate acyltransferase 4 (GPAT4), also known as AGPAT6, is a novel glycerolipid acyltransferase of the ER, which is crucial for the production of milk fat by the mammary gland.

Agpat6 deficiency leads to a reduction in body weight and resistance to both diet-induced and genetically induced obesity. This reduced body weight is associated with increased energy expenditure, reduced triglyceride accumulation in BAT and WAT, reduced white adipocyte size, and lack of adipose tissue in the subdermal region. AGPAT6 fills a unique role in determining triglyceride content and composition in adipose tissue and liver that cannot be compensated by other members of the Agpat family.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol AGPAT6