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ACE/CD143 Antibody (230214) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, IP, CyTOF-ready
Clone
230214
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 585

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB15131U-100UG
Alexa Fluor 405
FAB15131V-100UG
Alexa Fluor 488
FAB15131G-100UG
Alexa Fluor 532
FAB15131X
Alexa Fluor 594
FAB15131T-100UG
Alexa Fluor 647
FAB15131R-100UG
Alexa Fluor 700
FAB15131N-100UG
Alexa Fluor 750
FAB15131S-100UG
Allophycocyanin
FAB15131A
Allophycocyanin/Cy7
FAB15131APCCY7
Biotin
FAB15131B
CoraFluor 1
FAB15131CL1
DyLight 350
FAB15131D
DyLight 405
FAB15131E
DyLight 488
FAB15131K
DyLight 550
FAB15131L
DyLight 594
FAB15131M
DyLight 650
FAB15131W
DyLight 680
FAB15131Y
DyLight 755
FAB15131Z
FITC
FAB15131F
HRP
FAB15131H
Janelia Fluor 525
FAB15131JF525
Janelia Fluor 549
FAB15131I
Janelia Fluor 635
FAB15131JF635
Janelia Fluor 646
FAB15131J
Janelia Fluor 669
FAB15131JF669
PE
FAB15131P
PE/Atto594
FAB15131PEATT594
PE/Cy5.5
FAB15131PECY55
PE/Cy7
FAB15131PECY7
PerCP
FAB15131C
Unconjugated
MAB15131
mFluor Violet 450 SE
FAB15131MFV450
mFluor Violet 500 SE
FAB15131MFV500
mFluor Violet 610 SE
FAB15131MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB15131
Carrier Free
MAB15131
Carrier Free
MAB15131-SP
Carrier Free
FAB15131V-100UG
Carrier Free
FAB15131U-100UG
Carrier Free
FAB15131T-100UG
Carrier Free
FAB15131S-100UG
Carrier Free
FAB15131R-100UG
Carrier Free
FAB15131N-100UG
Carrier Free
FAB15131G-100UG
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ACE/CD143 Antibody (230214) [Janelia Fluor® 585] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse ACE/CD143
Leu35-Glu1264
Accession # P09470
Specificity
Detects mouse ACE/CD143.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
ACE
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ACE/CD143 Antibody (230214) [Janelia Fluor® 585]

  • ACE
  • ACE1angiotensin converting enzyme, somatic isoform
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • carboxycathepsin
  • CD143 antigen
  • CD143
  • DCP
  • DCP1
  • DCP1angiotensin-converting enzyme
  • dipeptidyl carboxypeptidase 1
  • Dipeptidyl carboxypeptidase I
  • EC 3.2.1.-
  • EC 3.4.15.1
  • Kininase II
  • MGC26566
  • MVCD3
  • peptidase P
  • testicular ECA

Background

ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ACE