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ACBP Antibody (C6)

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Product Details

Summary
Reactivity Hu, Rt, PoSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
C6
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

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ACBP Antibody (C6) Summary

Immunogen
Immunized with recombinant Human ACBP (Uniprot#: P07108; Met1-Ile104 (Uniprot#: P07108)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
DBI
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 5-20ug/mL
  • Immunohistochemistry 5-20ug/mL
  • Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.01M PBS, pH7.4, 50% glycerol
Preservative
0.05% Proclin 300
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for ACBP Antibody (C6)

  • ACBP
  • acyl-Coenzyme A binding domain containing 1
  • acyl-Coenzyme A bindingprotein)
  • CCK-RP
  • cholecystokinin-releasing peptide, trypsin-sensitive
  • DBI
  • diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
  • Diazepam-binding inhibitor
  • Endozepine
  • EP
  • GABA receptor modulator
  • MGC70414

Background

ACBP encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. ACBP is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for ACBP Antibody (NBP3-41686) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DBI