Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu, Mu
Applications: WB
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
PIAS1 encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
8554 |
Alternate Names |
- AR interacting protein
- DDXBP1MGC141878
- DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1
- DEAD/H box-binding protein 1
- E3 SUMO-protein ligase PIAS1
- GBPRNA helicase II-binding protein
- GU/RH-II
- Gu-binding protein
- MGC141879
- Protein inhibitor of activated STAT protein 1
- protein inhibitor of activated STAT, 1
- protein inhibitor of activated STAT-1
- zinc finger, MIZ-type containing 3
- ZMIZ3
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Research Areas for PIAS1
Find related products by research area and learn more about each of the different research areas below.
Signal Transduction