Species: Hu, Mu
Applications: WB, IHC, IP, ChIP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IP, KD
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
PHF8 (PHD finger protein 8) is a member of the jumonji family of proteins and contains a jumonji C (JmjC) domain. The JmjC proteins are predicted to be metalloenzymes that play a role a chromatin remodeling and histone demethylation. PHF8 also bears a PHD (plant homeodomain)- type zinc-finger, a domain also found to be involved in chromatin remodeling and transcriptional regulation. Truncating mutations in PHF8 are associated with X-linked mental retardation and cleft lip/cleft palate. PHF8 is also known as ZNF422 and KIAA1111.
Bioinformatics
| Uniprot |
Human
|
| Product By Gene ID |
23133 |
| Alternate Names |
- EC 1.14.11.27
- histone lysine demethylase PHF8
- jumonji C domain-containing histone demethylase 1F
- KIAA1111ZNF422JHDM1F
- MRXSSD
- PHD finger protein 8DKFZp686E0868
|
