Species: Hu, Mu
Applications: IHC
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA, IHC
Host: Sheep Polyclonal
Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Rt
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Description
FUNCTION: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity (By similarity). SUBCELLULAR LOCATION: Endoplasmic reticulum; rough endoplasmic reticulum (By similarity). Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses (By similarity). SIMILARITY: Belongs to the orexin family.
Bioinformatics
| Uniprot |
Human
Human
|
| Product By Gene ID |
3060 |
| Alternate Names |
- hypocretin (orexin) neuropeptide precursor
- NRCLP1
- orexin
- OXHcrt
- PPORX
- PPOXHypocretin
|
![Immunohistochemistry Orexin A/Hypocretin-1 Antibody (97505) [Unconjugated]](http://images.novusbio.com/fullsize2/mab763_human-mouse-rat-orexin-a-hypocretin-1-mab-clone-97505-immunohistochemistry-30112022115129.jpg)
