Species: Hu, Mu, Rt
Applications: WB, Flow, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Xp
Applications: WB
Host: Rabbit Polyclonal
Species: Hu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
The protein encoded by the MAL gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. (provided by RefSeq)
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
4118 |
Alternate Names |
- mal, T-cell differentiation protein
- myelin and lymphocyte protein
- T-cell differentiation protein MAL
- T-lymphocyte maturation-associated protein
|
Research Areas for MAL
Find related products by research area and learn more about each of the different research areas below.
Apoptosis