Species: Hu, Mu, Rt, Bv
Applications: WB, ELISA, ICC/IF, IHC, KD
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Bv, Ca, Pm, Eq, Pm, Pm-Or, Pm, Rb
Applications: WB, ICC/IF, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
REDD1 (regulated in development and DNA damage response 1) is a direct transcriptional target of HIF. It plays a role in the TSC/mTOR pathway as a regulator upstream of the TSC1/2 complex. In response to both hypoxia and energy stress, REDD1 inhibits mTOR activity in a TSC-dependent manner.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
54541 |
Alternate Names |
- Dig2
- DNA-damage-inducible transcript 4
- FLJ20500
- HIF-1 responsive RTP801 (RTP801)
- Protein regulated in development and DNA damage response 1
- REDD-1DNA damage-inducible transcript 4 protein
- REDD1HIF-1 responsive protein RTP801
- RTP801RP11-442H21.1
|
Research Areas for DDIT4
Find related products by research area and learn more about each of the different research areas below.
CancermTOR Pathway