Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Glycerol-3-phosphate acyltransferase 4 (GPAT4), also known as AGPAT6, is a novel glycerolipid acyltransferase of the ER, which is crucial for the production of milk fat by the mammary gland.
Agpat6 deficiency leads to a reduction in body weight and resistance to both diet-induced and genetically induced obesity. This reduced body weight is associated with increased energy expenditure, reduced triglyceride accumulation in BAT and WAT, reduced white adipocyte size, and lack of adipose tissue in the subdermal region. AGPAT6 fills a unique role in determining triglyceride content and composition in adipose tissue and liver that cannot be compensated by other members of the Agpat family.
Bioinformatics
| Entrez |
Mouse
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
137964 |
| Alternate Names |
- 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acidacyltransferase, zeta)
- Acyl-CoA:glycerol-3-phosphate acyltransferase 4
- DKFZp586M1819,1-acyl-sn-glycerol-3-phosphate acyltransferase zeta
- EC 2.3.1.15
- glycerol-3-phosphate acyltransferase 4,1-AGP acyltransferase 6
- glycerol-3-phosphate acyltransferase 6,1-AGPAT 6
- GPAT4,1-acylglycerol-3-phosphate O-acyltransferase 6
- LPAAT-zetaLPAATZ
- Lysophosphatidic acid acyltransferase zeta
- testis spermatogenesis apoptosis-related protein 7
- TSARG7
|
