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CD3ZETA

Cluster of Differentiation 3 (CD3) (OKT3 clone) as a Marker of Immune Response Efficiency

Our immune system is a powerful defense mechanism against infection, however different variables can cause our immune response to work for or against us.  CD3 (cluster of differentiation 3) is one component of our immune signal response that is composed of four distinct chains (CD3-g, CD3-e, CD3-s and the zeta chain). These chains associate with a molecule known as the T-cell receptor (TCR) to comprise the TCR complex.